Steven R. Skinner

Design, synthesis and selection of DNA-encoded small-molecule libraries

Matthew Clark, Raksha Acharya, Christopher C. Arico-Muendel et al. · Nature Chemical Biology · 2009 · 691 citations · Full text

Pharmacy, Biotechnology, Medicinal Chemistry +12

Discovery of Highly Potent and Selective Small Molecule ADAMTS-5 Inhibitors That Inhibit Human Cartilage Degradation via Encoded Library Technology (ELT)

Hongfeng Deng, Heather P. O’Keefe, Christopher P. Davie et al. · Journal of Medicinal Chemistry · 2012 · 149 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Application of encoded library technology (ELT) to a protein–protein interaction target: Discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists

Christopher S. Kollmann, Xiaopeng Bai, Ching-Hsuan Tsai et al. · Bioorganic & Medicinal Chemistry · 2014 · 96 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

Discovery of Potent and Selective Inhibitors for ADAMTS-4 through DNA-Encoded Library Technology (ELT)

Yun Ding, Heather P. O’Keefe, Jennifer L. DeLorey et al. · ACS Medicinal Chemistry Letters · 2015 · 77 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery of a Potent Class of PI3Kα Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT)

Hongfang Yang, Patrícia Flores de Medeiros, Kaushik Raha et al. · ACS Medicinal Chemistry Letters · 2015 · 75 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17