Hongfang Yang

Encoded Library Technology as a Source of Hits for the Discovery and Lead Optimization of a Potent and Selective Class of Bactericidal Direct Inhibitors of <i>Mycobacterium tuberculosis</i> InhA

Lourdes Encinas, Heather P. O’Keefe, Margarete Neu et al. · Journal of Medicinal Chemistry · 2014 · 118 citations · Full text

Bioorganic Chemistry, Hit Identification, Pharmaceutical Chemistry +22

Ionic liquids via reaction of the zwitterionic 1,3-dimethylimidazolium-2-carboxylate with protic acids. Overcoming synthetic limitations and establishing new halide free protocols for the formation of ILs

Marcin Śmiglak, John D. Holbrey, Scott T. Griffin et al. · Green Chemistry · 2006 · 97 citations

Engineering, Green Chemistry, Organic Chemistry +16

Application of encoded library technology (ELT) to a protein–protein interaction target: Discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists

Christopher S. Kollmann, Xiaopeng Bai, Ching-Hsuan Tsai et al. · Bioorganic & Medicinal Chemistry · 2014 · 96 citations · Full text

Potent Class, Medicine, Immunology +6

Hydrogenolysis of Lignin Model Compounds on Ni Nanoparticles Surrounding the Oxygen Vacancy of CeO₂

Jin Xie, Yongjie Xi, Wensheng Gao et al. · ACS Catalysis · 2023 · 77 citations

Materials Science, Oxygen Vacancy, Chemical Engineering +13

Discovery of a Potent Class of PI3Kα Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT)

Hongfang Yang, Patrícia Flores de Medeiros, Kaushik Raha et al. · ACS Medicinal Chemistry Letters · 2015 · 74 citations · Full text

Molecular Docking, Drug Target, Biochemistry +15