Crosstalk between the Type 1 Interferon and Nuclear Factor Kappa B Pathways Confers Resistance to a Lethal Virus Infection

Daniel Rubio, Ren-Huan Xu, Sanda Remakus, +7

Cell Host & Microbe

Type 1Molecular VirologyPathogenesisViral PathogenesisImmunology +5

Targeted Blockade of JAK/STAT3 Signaling Inhibits Ovarian Carcinoma Growth

Galina Gritsina, Fang Xiao, Shane W. O’Brien, +11

Molecular Cancer Therapeutics

ImmunologyGynecologyCancer BiologyTumor BiologyOvarian Cancer +15

The orthopoxvirus type I IFN binding protein is essential for virulence and an effective target for vaccination

Ren-Huan Xu, Matthew E. Cohen, Yong Tang, +5

The Journal of Experimental Medicine

Viral PathogenesisImmunologyImmunotherapyEffective TargetVaccine Target +14

Sequential Activation of Two Pathogen-Sensing Pathways Required for Type I Interferon Expression and Resistance to an Acute DNA Virus Infection

Ren-Huan Xu, Eric B. Wong, Daniel Rubio, +8

Immunity

Molecular VirologyPathogenesisViral PathogenesisImmunologyPathogen-sensing Pathways +8

Direct Presentation Is Sufficient for an Efficient Anti-Viral CD8+ T Cell Response

Ren-Huan Xu, Sanda Remakus, Xueying Ma, +2

PLoS Pathogens

Memory CD8⁺T cells are gatekeepers of the lymph node draining the site of viral infection

Ren-Huan Xu, Min Fang, Andres J. Klein–Szanto, +1

Proceedings of the National Academy of Sciences

Persistent VirusAdaptive Immune SystemT CellsImmune RegulationImmunology +13

Migratory Dendritic Cells, Group 1 Innate Lymphoid Cells, and Inflammatory Monocytes Collaborate to Recruit NK Cells to the Virus-Infected Lymph Node

Eric B. Wong, Ren-Huan Xu, Daniel Rubio, +4

Cell Reports

Langerhans Cells Orchestrate the Protective Antiviral Innate Immune Response in the Lymph Node

Eric B. Wong, Brian Montoya, Colby Stotesbury, +3

Cell Reports

Memory CD8 + T Cells Can Outsource IFN-γ Production but Not Cytolytic Killing for Antiviral Protection

Sanda Remakus, Daniel Rubio, Avital Lev, +4

Cell Host & Microbe

Antiviral ProtectionCytolytic KillingAdaptive Immune SystemImmunologyAntiviral Response +9

HER2-LAMP vaccines effectively traffic to endolysosomal compartments and generate enhanced polyfunctional T cell responses that induce complete tumor regression

Alan Chen Chen, Ren-Huan Xu, Tao Wang, +7

Journal for ImmunoTherapy of Cancer