Concepedia

Sequential Activation of Two Pathogen-Sensing Pathways Required for Type I Interferon Expression and Resistance to an Acute DNA Virus Infection

Ren-Huan Xu, Eric B. Wong, Daniel Rubio, Felicia Roscoe, Xueying Ma, Savita Nair, Sanda Remakus, Reto A. Schwendener, Shinu John, Mark J. Shlomchik,

Immunity · 2015 · 69 citations · 46 references

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46

A Toll-like receptor recognizes bacterial DNA

Hiroaki Hemmi, Osamu Takeuchi, Taro Kawai et al. · Nature · 2000 · 6.4K citations

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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Hiroki Ishikawa, Glen N. Barber · Nature · 2008 · 3.5K citations · Full text

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Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function

Osamu Adachi, Taro Kawai, Kiyoshi Takeda et al. · Immunity · 1998 · 2K citations · Full text

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Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

Emmanuel L. Gautier, Tal Shay, Jennifer Miller et al. · Nature Immunology · 2012 · 2K citations · Full text

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IRAK (Pelle) Family Member IRAK-2 and MyD88 as Proximal Mediators of IL-1 Signaling

Marta Muzio, Jian Ni, Ping Feng et al. · Science · 1997 · 1.2K citations

, , +17