John Deadman

Parallel Screening of Low Molecular Weight Fragment Libraries: Do Differences in Methodology Affect Hit Identification?

J. Wielens, Stephen J. Headey, David I. Rhodes et al. · SLAS DISCOVERY · 2012 · 75 citations · Full text

Binaphthyl‐Based Dicationic Peptoids with Therapeutic Potential

John B. Bremner, Paul A. Keller, Stephen G. Pyne et al. · Angewandte Chemie International Edition · 2009 · 61 citations

Small Molecule Inhibitors of the LEDGF Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design

Thomas S. Peat, David I. Rhodes, Nick Vandegraaff et al. · PLoS ONE · 2012 · 52 citations · Full text

Small Molecule Inhibitors, Molecular Biology, Ledgf Site +19

Structural Basis for a New Mechanism of Inhibition of H I V-1 Integrase Identified by Fragment Screening and Structure-Based Design

David I. Rhodes, Thomas S. Peat, Nick Vandegraaff et al. · Antiviral chemistry & chemotherapy · 2011 · 50 citations

Preferential antagonism of the interactions of the integrin <i>α</i>IIb<i>β</i>3 with immobilized glycoprotein ligands by snake-venom RGD (Arg-Gly-Asp) proteins. Evidence supporting a functional role for the amino acid residues flanking the tripeptide RGD in determining the inhibitory properties of snake-venom RGD proteins

Xin Lü, John A. Williams, John Deadman et al. · Biochemical Journal · 1994 · 48 citations · Full text

Protein Function, Biochemistry, Medicine +15