J. Wielens - Concepedia

Author

J. Wielens

St Vincents Institute of Medical Research ORCID

Also Known As

J Wielens, J. Wielens, Jerome Wielens, Wielens, Jerome

Publications

921

Citations

H-Index

Concepts

All Affiliations

St Vincents Institute of Medical Research Monash University The University of Melbourne The University of Sydney Novita Healthcare (Australia)

About

J. Wielens is an author at St Vincents Institute of Medical Research specializing in medicine, natural sciences, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	6	6	284
2	Natural Sciences	5	5	230
3	Biochemistry	4	4	201
4	Biomolecular Engineering	1	1	10
5	Cell Biology	1	1	29

J. Wielens

Publications

607

Citations

H-Index

Page 1

	Year	Citations
Potent hepatitis C inhibitors bind directly to NS5A and reduce its affinity for RNA David B. Ascher, J. Wielens, Tracy L. Nero, Scientific Reports Hcv Protein Ns5aBiochemistryHepatitis C VirusViral HepatitisMedicine	2014	114
Parallel Screening of Low Molecular Weight Fragment Libraries: Do Differences in Methodology Affect Hit Identification? J. Wielens, Stephen J. Headey, David I. Rhodes, SLAS DISCOVERY	2012	75
The Structure of the Bacterial Oxidoreductase Enzyme DsbA in Complex with a Peptide Reveals a Basis for Substrate Specificity in the Catalytic Cycle of DsbA Enzymes Jason J. Paxman, Natalie A. Borg, James Horne, Journal of Biological Chemistry	2009	74
The Interaction of Lipophilic Drugs with Intestinal Fatty Acid-binding Protein Tony Velkov, Sara Chuang, J. Wielens, Journal of Biological Chemistry Drug-i-fabp Interaction InterfacesMedicinal ChemistryDrug AnalysisDrug TargetLipid Synthesis	2005	62
A Three-dimensional Model of the Human Immunodeficiency Virus Type 1 Integration Complex J. Wielens, Ian T. Crosby, David K. Chalmers Journal of Computer-Aided Molecular Design Three-dimensional ModelHuman RetrovirusImmunologyAntiviral ResponseVirology	2005	54
Crystal structure of the HIV‐1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site J. Wielens, Stephen J. Headey, Dharshini Jeevarajah, FEBS Letters	2010	41
Characterization of Two Distinct Modes of Drug Binding to Human Intestinal Fatty Acid Binding Protein Rahul Patil, Aisha Laguerre, J. Wielens, ACS Chemical Biology	2014	35
Phosphorylation of syndapin I F-BAR domain at two helix-capping motifs regulates membrane tubulation Annie Quan, Jing Xue, J. Wielens, Proceedings of the National Academy of Sciences Protein SecretionMolecular BiologyAnalytical UltracentrifugationSynaptic SignalingMembrane Tubulation	2012	29
Structural and Biochemical Characterization of the Oxidoreductase NmDsbA3 from Neisseria meningitidis J.P. Vivian, Jessica Scoullar, Amy L. Robertson, Journal of Biological Chemistry	2008	28
Fragment‐Based Design of Ligands Targeting a Novel Site on the Integrase Enzyme of Human Immunodeficiency Virus 1 J. Wielens, Stephen J. Headey, John Deadman, ChemMedChem	2010	26

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