David K. Chalmers

Free Energy Methods in Drug Design: Prospects of “Alchemical Perturbation” in Medicinal Chemistry

Billy J. Williams‐Noonan, Elizabeth Yuriev, David K. Chalmers · Journal of Medicinal Chemistry · 2017 · 165 citations

Pharmacy, Chemistry, Medicinal Chemistry +16

Discovery of 7-Hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[<i>b</i>]furan (BNC105), a Tubulin Polymerization Inhibitor with Potent Antiproliferative and Tumor Vascular Disrupting Properties

Bernard L. Flynn, Gurmit S. Gill, Damian Grobelny et al. · Journal of Medicinal Chemistry · 2011 · 139 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Pro-D-NMe-Amino Acid and D-Pro-NMe-Amino Acid: Simple, Efficient Reverse-Turn Constraints

David K. Chalmers, Garland R. Marshall · Journal of the American Chemical Society · 1995 · 136 citations

Pharmacy, Biochemistry, Drug Design +5

Comparisons of the Hbv and HIV Polymerase, and Antiviral Resistance Mutations

Angeline Bartholomeusz, Benjamin G. Tehan, David K. Chalmers · Antiviral Therapy · 2004 · 120 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

Molecular dynamics simulations of spontaneous bile salt aggregation

Dallas B. Warren, David K. Chalmers, Keith Hutchison et al. · Colloids and Surfaces A Physicochemical and Engineering Aspects · 2006 · 105 citations

Natural Sciences, Biophysics, Physics +14