Billy J. Williams‐Noonan

Free Energy Methods in Drug Design: Prospects of “Alchemical Perturbation” in Medicinal Chemistry

Billy J. Williams‐Noonan, Elizabeth Yuriev, David K. Chalmers · Journal of Medicinal Chemistry · 2017 · 161 citations

Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry

Hoan Vu, Liliana Pedro, Tin Mak et al. · ACS Infectious Diseases · 2018 · 61 citations · Full text

Drug Target, Malaria, Molecular Biology +19

Improving Membrane Permeation in the Beyond Rule-of-Five Space by Using Prodrugs to Mask Hydrogen Bond Donors

Νicholas Barlow, David K. Chalmers, Billy J. Williams‐Noonan et al. · ACS Chemical Biology · 2020 · 43 citations · Full text

Proteinlipid Interaction, Hydrogen Bond Acceptors, Membrane Formation +13

Self-assembling peptide biomaterials: Insights from spontaneous and enhanced sampling molecular dynamics simulations

Billy J. Williams‐Noonan, Alexa Kamboukos, Nevena Todorova et al. · Chemical Physics Reviews · 2023 · 36 citations · Full text

Supramolecular Assembly, Engineering, Peptide Engineering +18

An Active Site Inhibitor Induces Conformational Penalties for ACE2 Recognition by the Spike Protein of SARS-CoV-2

Billy J. Williams‐Noonan, Nevena Todorova, Ketav Kulkarni et al. · The Journal of Physical Chemistry B · 2021 · 35 citations

Engineering, Ace2 Recognition, Immunology +26