Νicholas Barlow

Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief

Dane D. Jensen, TinaMarie Lieu, Michelle L. Halls et al. · Science Translational Medicine · 2017 · 241 citations · Full text

Life Sciences, Neuroscience, Pharmacology +15

Cathepsin S Causes Inflammatory Pain via Biased Agonism of PAR2 and TRPV4

Peishen Zhao, TinaMarie Lieu, Νicholas Barlow et al. · Journal of Biological Chemistry · 2014 · 185 citations · Full text

Life Sciences, Chemical Biology, Cell Signaling +11

Neutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain

Peishen Zhao, TinaMarie Lieu, Νicholas Barlow et al. · Journal of Biological Chemistry · 2015 · 168 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Dynamic binding mode of a Synaptotagmin-1–SNARE complex in solution

Kyle D. Brewer, Taulant Bacaj, Andrea Cavalli et al. · Nature Structural & Molecular Biology · 2015 · 154 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

DOTA-Amide Lanthanide Tag for Reliable Generation of Pseudocontact Shifts in Protein NMR Spectra

Bim Graham, Choy Theng Loh, James Swarbrick et al. · Bioconjugate Chemistry · 2011 · 120 citations

Life Sciences, Biochemistry, Biophysics +15