DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

Yosuke Harada, Yoshihiko Tanaka, Masao Terasawa, +15

Blood

Malaria Parasites Require TLR9 Signaling for Immune Evasion by Activating Regulatory T Cells

Hajime Hisaeda, Kohhei Tetsutani, Takashi Imai, +15

The Journal of Immunology

Involvement of CD8⁺ T cells in protective immunity against murine blood‐stage infection with <i>Plasmodium yoelii</i> 17XL strain

Takashi Imai, Jianying Shen, Bin Chou, +9

European Journal of Immunology

Adaptive Immune SystemMalariaImmunologyImmunologic MechanismCd4 T Cell Responses +16

Blockade of Inflammatory Responses by a Small-Molecule Inhibitor of the Rac Activator DOCK2

Akihiko Nishikimi, Takehito Uruno, Xuefeng Duan, +20

Chemistry & Biology

InflammationInflammatory ResponsesAnti-inflammatoryRac Activator Dock2Medicine +10

The AP-1 transcription factor JunB is required for Th17 cell differentiation

Soh Yamazaki, Yoshihiko Tanaka, Hiromitsu Araki, +12

Scientific Reports

The Rac activator DOCK2 regulates natural killer cell–mediated cytotoxicity in mice through the lytic synapse formation

Yusuke Sakai, Yoshihiko Tanaka, Toyoshi Yanagihara, +6

Blood

DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation

Kana Ogawa, Yoshihiko Tanaka, Takehito Uruno, +8

The Journal of Experimental Medicine

SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2ZYG11B activity

Liying Wang, Chao Liu, Bo Yang, +21

The Journal of Cell Biology

Cul2zyg11b ActivitySignal TransductionInflammatory Lung DiseaseAllergyLung Inflammation +13

Critical role for the immunoproteasome subunit LMP7 in the resistance of mice to <i>Toxoplasma gondii</i> infection

Liping Tu, Chikako Moriya, Takashi Imai, +8

European Journal of Immunology

ImmunologyImmunodominanceImmunologic MechanismAntigen ProcessingImmune System +15

FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer

Dongying Wang, Shuying Wu, Jiaxing He, +7

Journal of Experimental & Clinical Cancer Research