Chengcan Yang

Main active components of Si-Miao-Yong-An decoction (SMYAD) attenuate autophagy and apoptosis via the PDE5A-AKT and TLR4-NOX4 pathways in isoproterenol (ISO)-induced heart failure models

Minru Liao, Qiang Xie, Yuqian Zhao et al. · Pharmacological Research · 2022 · 94 citations

Life Sciences, Molecular Biology, Pharmacology +17

MCDB: A comprehensive curated mitotic catastrophe database for retrieval, protein sequence alignment, and target prediction

Le Zhang, Lei Zhang, Ming Xiao et al. · Acta Pharmaceutica Sinica B · 2021 · 52 citations · Full text

Medicine, Bioinformatics, Molecular Biology +17

Discovery of 4-Hydroxyquinazoline Derivatives as Small Molecular BET/PARP1 Inhibitors That Induce Defective Homologous Recombination and Lead to Synthetic Lethality for Triple-Negative Breast Cancer Therapy

Jifa Zhang, Chengcan Yang, Pan Tang et al. · Journal of Medicinal Chemistry · 2022 · 48 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +14

Targeting Bromodomain-Selective Inhibitors of BET Proteins in Drug Discovery and Development

Juncheng Chen, Pan Tang, Yuxi Wang et al. · Journal of Medicinal Chemistry · 2022 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Discovery, Synthesis, and Evaluation of Highly Selective Vascular Endothelial Growth Factor Receptor 3 (VEGFR3) Inhibitor for the Potential Treatment of Metastatic Triple-Negative Breast Cancer

Yang Li, Gaoxia Yang, Jifa Zhang et al. · Journal of Medicinal Chemistry · 2021 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14