Jonathan Cooper

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia

Konstantinos Tzelepis, Hiroko Koike-Yusa, Étienne De Braekeleer et al. · Cell Reports · 2016 · 784 citations · Full text

Gene Deletion Data, Genetics, Acute Myeloid Leukemia +9

Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice

George S. Vassiliou, Jonathan Cooper, Roland Rad et al. · Nature Genetics · 2011 · 226 citations · Full text

Chromatin, Genome Instability, Molecular Pathway +9

UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs

Malgorzata Gozdecka, Eshwar Meduri, Milena Mazan et al. · Nature Genetics · 2018 · 156 citations · Full text

Hematological Malignancy, Chromatin, Systems Biology +9

The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

Dimitrios Papaioannou, Andreas Petri, Oliver M. Dovey et al. · Nature Communications · 2019 · 156 citations · Full text

Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia

Oliver M. Dovey, Jonathan Cooper, Annalisa Mupo et al. · Blood · 2017 · 93 citations · Full text