Peter J. Elliott

Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

Marie Lagouge, Carmen Argmann, Zachary Gerhart‐Hines et al. · Cell · 2006 · 4K citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Carles Cantó, Zachary Gerhart‐Hines, Jérôme N. Feige et al. · Nature · 2009 · 3.2K citations · Full text

Life Sciences, Biochemistry, Cell Biology +15

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Jill C. Milne, Philip Lambert, Simon Schenk et al. · Nature · 2007 · 1.7K citations · Full text

Medicine, Medicinal Chemistry, Molecular Biology +14

The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells.

Teru Hideshima, Paul G. Richardson, D Chauhan et al. · PubMed · 2001 · 1.5K citations

Medicine, Oncology, Pharmacology +17

Proteasome inhibitors: a novel class of potent and effective antitumor agents.

Julian Adams, Vito J. Palombella, Edward A. Sausville et al. · PubMed · 1999 · 1.5K citations

Medicine, Oncology, Pharmacology +14