Steve Tam

Synthesis and Biological Evaluation of Quinoline Salicylic Acids As P-Selectin Antagonists

Neelu Kaila, Kristin Janz, Silvano DeBernardo et al. · Journal of Medicinal Chemistry · 2006 · 122 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Potent, selective, and orally bioavailable matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis

Yonghan Hu, Jason Xiang, Martin J. DiGrandi et al. · Bioorganic & Medicinal Chemistry · 2005 · 108 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9

A Selective Matrix Metalloprotease 12 Inhibitor for Potential Treatment of Chronic Obstructive Pulmonary Disease (COPD): Discovery of (<i>S</i>)-2-(8-(Methoxycarbonylamino)dibenzo[<i>b</i>,<i>d</i>]furan-3-sulfonamido)-3-methylbutanoic acid (MMP408)

Wei Li, Jianchang Li, Yuchuan Wu et al. · Journal of Medicinal Chemistry · 2009 · 104 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Synthesis and biological evaluation of sulfonamidooxazoles and β-keto sulfones: selective inhibitors of 11β-hydroxysteroid dehydrogenase type I

Jason Xiang, Manus Ipek, Vipin Suri et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 86 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

2-(4-Chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[<i>H</i>]quinoline-4-carboxylic Acid (PSI-697):  Identification of a Clinical Candidate from the Quinoline Salicylic Acid Series of P-Selectin Antagonists

Neelu Kaila, Kristin Janz, Adrian Huang et al. · Journal of Medicinal Chemistry · 2006 · 83 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16