Ewald Edink

Fragment Growing Induces Conformational Changes in Acetylcholine-Binding Protein: A Structural and Thermodynamic Analysis

Ewald Edink, Prakash Rucktooa, Kim Retra et al. · Journal of the American Chemical Society · 2011 · 81 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

Conjugation of Penicillin Acylase with the Reactive Copolymer of N-Isopropylacrylamide: A Step Toward a Thermosensitive Industrial Biocatalyst

Alexander E. Ivanov, Ewald Edink, Ashok Kumar et al. · Biotechnology Progress · 2003 · 61 citations

Life Sciences, Biochemistry, Biotechnology +17

4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA–PB1 Protein–Protein Interaction: Structure–Activity Relationships Exploration with the Aid of Molecular Modeling

Iuni Margaret Laura Trist, Giulio Nannetti, Cristina Tintori et al. · Journal of Medicinal Chemistry · 2016 · 56 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Targeting a Subpocket in <i>Trypanosoma brucei</i> Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity

Antoni R. Blaazer, Abhimanyu K. Singh, Erik de Heuvel et al. · Journal of Medicinal Chemistry · 2018 · 43 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis and evaluation of analogs of the phenylpyridazinone NPD-001 as potent trypanosomal TbrPDEB1 phosphodiesterase inhibitors and in vitro trypanocidals

Johan J. N. Veerman, Toine van den Bergh, Kristina M. Orrling et al. · Bioorganic & Medicinal Chemistry · 2016 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9