Erik de Heuvel

Discovery of Small Molecule Vanin Inhibitors: New Tools To Study Metabolism and Disease

Patrick A.M. Jansen, Janna A. van Diepen, Bas Ritzen et al. · ACS Chemical Biology · 2012 · 54 citations · Full text

Drug Target, Competitive Vanin Inhibitor, Chemical Biology +21

Targeting a Subpocket in <i>Trypanosoma brucei</i> Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity

Antoni R. Blaazer, Abhimanyu K. Singh, Erik de Heuvel et al. · Journal of Medicinal Chemistry · 2018 · 43 citations · Full text

Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2)

Erik de Heuvel, Abhimanyu K. Singh, Pierre Boronat et al. · Bioorganic & Medicinal Chemistry · 2019 · 19 citations · Full text

Stable pantothenamide bioisosteres: novel antibiotics for Gram-positive bacteria

Patrick A.M. Jansen, Danique A. van der Krieken, Peter N. M. Botman et al. · The Journal of Antibiotics · 2019 · 18 citations · Full text

Plasma-stable Pantothenamide Analogs, Antibiotics, Multidrug Resistant Bacteria +11

Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors

Erik de Heuvel, Abhimanyu K. Singh, Ewald Edink et al. · Bioorganic & Medicinal Chemistry · 2019 · 18 citations · Full text

Antiparasitic Agent, Molecular Biology, Organic Chemistry +21