J. Russell Lipford

The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity

Jude Canon, Karen Rex, Anne Y. Saiki et al. · Nature · 2019 · 2.3K citations

Medicine, Oncology, Pharmacology +14

Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

Christian Bronner, Sean M. Baker, Paul T. Morrison et al. · Nature · 1994 · 2.1K citations

Life Sciences, Genetics, Molecular Genetics +12

KRAS ^G12C Inhibition with Sotorasib in Advanced Solid Tumors

David S. Hong, Marwan Fakih, John H. Strickler et al. · New England Journal of Medicine · 2020 · 1.7K citations · Full text

Medicine, Oncology, Oncogenes +1

Discovery of a Covalent Inhibitor of KRAS^G12C (AMG 510) for the Treatment of Solid Tumors

Brian A. Lanman, Jennifer R. Allen, John G. Allen et al. · Journal of Medicinal Chemistry · 2019 · 722 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +16

Diverse alterations associated with resistance to KRAS(G12C) inhibition

Yulei Zhao, Yonina R. Murciano‐Goroff, Jenny Y. Xue et al. · Nature · 2021 · 447 citations · Full text

Medicine, Molecular Biology, Molecular Genetics +10