Xihan Wu

Discovery of Small-Molecule Inhibitors of Bcl-2 through Structure-Based Computer Screening

Istvan Enyedy, Yan Ling, Kassoum Nacro et al. · Journal of Medicinal Chemistry · 2001 · 312 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +12

Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-XL [(−)-gossypol] against diffuse large cell lymphoma

Ramzi M. Mohammad, Shaomeng Wang, Amro Aboukameel et al. · Molecular Cancer Therapeutics · 2005 · 141 citations · Full text

Medicine, Oncology, Pharmacology +13

<b> <i>In vitro</i> </b> Effects of the BH3 Mimetic, (−)-Gossypol, on Head and Neck Squamous Cell Carcinoma Cells

Christopher L. Oliver, Joshua A. Bauer, Keith G. Wolter et al. · Clinical Cancer Research · 2004 · 134 citations

Medicine, Oncology, Pharmacology +13

Molecular Modeling of the Three-Dimensional Structure of Dopamine 3 (D₃) Subtype Receptor:  Discovery of Novel and Potent D₃Ligands through a Hybrid Pharmacophore- and Structure-Based Database Searching Approach

Judith Varady, Xihan Wu, Xueliang Fang et al. · Journal of Medicinal Chemistry · 2003 · 128 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Nonpeptidic Small-Molecule Inhibitor of Bcl-2 and Bcl-XL, (???)-Gossypol, Enhances Biological Effect of Genistein Against BxPC-3 Human Pancreatic Cancer Cell Line

Ramzi M. Mohammad, Shaomeng Wang, Sanjeev Banerjee et al. · Pancreas · 2005 · 66 citations

Medicine, Oncology, Pharmacology +13