CYP2C19 Genotype and Pharmacokinetics of Three Proton Pump Inhibitors in Healthy Subjects

Toshiyuki Sakai, Nobuo Aoyama, Tomoko Kita, +9

Pharmaceutical Research

Effect of micafungin on cytochrome P450 3A4 and multidrug resistance protein 1 activities, and its comparison with azole antifungal drugs

Toshiyuki Sakaeda, Koichi Iwaki, Mikio Kakumoto, +7

Journal of Pharmacy and Pharmacology

Cytochrome P450 3A4Drug Resistance AnalysisAntifungal AgentBiochemistryAntifungal Agents +13

Cytotoxic Effects of 27 Anticancer Drugs in HeLa and MDR1-Overexpressing Derivative Cell Lines.

Kohji Takara, Toshiyuki Sakaeda, Tatsurou Yagami, +5

Biological and Pharmaceutical Bulletin

Tumor BiologyCytotoxic EffectsTaxanes PaclitaxelOncologyDrug Resistance Analysis +12

Effects of Acid and Lactone Forms of Eight HMG-CoA Reductase Inhibitors on CYP-Mediated Metabolism and MDR1-Mediated Transport

Toshiyuki Sakaeda, Hideki Fujino, Chiho Komoto, +7

Pharmaceutical Research

Aldo-keto ReductaseBiochemistryMitochondrial FunctionMedicineCyp-mediated Metabolism +7

Cellular Pharmacokinetic Aspects of Reversal Effect of Itraconazole on P-Glycoprotein-Mediated Resistance of Anticancer Drugs.

Kohji Takara, Yusuke Tanigawara, Fusao Komada, +3

Biological and Pharmaceutical Bulletin

P-glycoprotein-mediated ResistanceHealth SciencesBiochemistryMedicineCellular Pharmacokinetic Aspects +12

Unbiased amplification of a highly complex mixture of DNA fragments by ‘lone linker’-tagged PCR

Minoru S.H. Ko, Shimamoto Ko, N. Takahashi, +2

Nucleic Acids Research

BiologyChromatinPolymerase Chain ReactionMedicineGenetics +13

The Structure-Activity Correlation on the Inhibitory Effects of Flavonoids on Cytochrome P450 3A Activity

Masayuki Tsujimoto, Maya Horie, Hiroko Honda, +2

Biological and Pharmaceutical Bulletin

PharmacotherapyQuantification TheoryPolyphenolicsOxidative StressCytochrome P450 3A +15

Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expression

Kohji Takara, Toshiyuki Sakaeda, Yusuke Tanigawara, +7

European Journal of Pharmaceutical Sciences

Ca2+ AntagonistsDrug Resistance AnalysisTranslational PharmacologyBiochemistryMedicine +7

Assessment of inhalation flow patterns of soft mist inhaler co-prescribed with dry powder inhaler using inspiratory flow meter for multi inhalation devices

Daiki Hira, Hiroyoshi Koide, Shigemi Nakamura, +12

PLoS ONE

AsthmaPulmonary CareInhalation Flow PatternMeasurementSoft Mist Inhaler +15

Replacement of cisplatin with nedaplatin in a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma

Akiko Kuwahara, Motohiro Yamamori, Kohshi Nishiguchi, +9

International Journal of Medical Sciences