Nobuo Aoyama

MDR1 Genotype-Related Pharmacokinetics of Digoxin After Single Oral Administration in Healthy Japanese Subjects

Toshiyuki Sakaeda, Tsutomu Nakamura, Masanori Horinouchi et al. · Pharmaceutical Research · 2001 · 321 citations

Medicine, Pharmacokinetics, Pharmacology +6

Effect of the mutation (C3435T) at exon 26 of the <i>MDR1</i> gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects

Tsutomu Nakamura, Toshiyuki Sakaeda, Masanori Horinouchi et al. · Clinical Pharmacology & Therapeutics · 2002 · 260 citations

Life Sciences, Genetics, Molecular Biology +12

Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori

Akihiro Fujikawa, Daisuke Shirasaka, Shoichi Yamamoto et al. · Nature Genetics · 2003 · 250 citations

Life Sciences, Biochemistry, Pathobiology +16

Primary Levofloxacin Resistance and <i>gyrA/B</i> Mutations Among <i>Helicobacter pylori</i> in Japan

Hideyuki Miyachi, Ikuya Miki, Nobuo Aoyama et al. · Helicobacter · 2006 · 141 citations

Life Sciences, Infectious Diseases, Microbiology +17

Real-Time Quantitative Polymerase Chain Reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA Levels in Caco-2 Cell Lines, Human Duodenal Enterocytes, Normal Colorectal Tissues, and Colorectal Adenocarcinomas

Tsutomu Nakamura, Toshiyuki Sakaeda, Nobuko Ohmoto et al. · Drug Metabolism and Disposition · 2002 · 137 citations

Medicine, Molecular Biology, Pharmacology +14