Safety of the oral factor XIa inhibitor asundexian compared with apixaban in patients with atrial fibrillation (PACIFIC-AF): a multicentre, randomised, double-blind, double-dummy, dose-finding phase 2 study

Jonathan P. Piccini, Valeria Caso, Stuart J. Connolly, +410

The Lancet

ThrombosisDose-finding Phase 2Cardiovascular DiseasePharmacologyCardiovascular Pharmacology +8

Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori

Akihiro Fujikawa, Daisuke Shirasaka, Shoichi Yamamoto, +9

Nature Genetics

Signal TransductionGastrointestinal PharmacologyPathogenesisImmunologyGastroenterology +7

MITOL/MARCH5 determines the susceptibility of cardiomyocytes to doxorubicin-induced ferroptosis by regulating GSH homeostasis

Hiroki Kitakata, Jin Endo, Hirokazu Matsushima, +17

Journal of Molecular and Cellular Cardiology

InflammationMitophagyCardiomyopathySignal TransductionMolecular Physiology +9

In vitro and in vivo studies on potentiation of cytotoxic effects of anticancer drugs or cobalt 60 gamma ray by interferon on human neoplastic cells

Masayoshi Namba, Shoichi Yamamoto, Hiroyoshi Tanaka, +3

Cancer

Phase I Clinical Studies of 7432‐S, a New Oral Cephalosporin: Safety and Pharmacokinetics

M Nakashima, Toshihiko Uematsu, Yoshiharu Takiguchi, +7

The Journal of Clinical Pharmacology

In vitro studies on potentiation of cytotoxic effects of anticancer drugs by interferon on a human neoplastic cell line (HeLa)

Shoichi Yamamoto, Hiroyoshi Tanaka, Toshinori Kanamori, +2

Cancer Letters

Cytotoxic EffectsOncologyMedicineImmunologyVitro Studies +7

Influence of the PsbA1/PsbA3, Ca2+/Sr2+ and Cl−/Br− exchanges on the redox potential of the primary quinone QA in Photosystem II from Thermosynechococcus elongatus as revealed by spectroelectrochemistry

Yuki Kato, Tadao Shibamoto, Shoichi Yamamoto, +5

Biochimica et Biophysica Acta (BBA) - Bioenergetics

BiochemistryPhotosystemsBioenergeticsPrimary Quinone QaBioelectrochemistry +9

Heat Transfer & Thermal Stress Analysis of Plastic-Encapsulated ICs

Kiyoshi Miyake, Hideto SUZUKI, Shoichi Yamamoto

IEEE Transactions on Reliability

Cross SectionEngineeringMechanical EngineeringAnalytic ApproachesAdvanced Packaging (Semiconductors) +15

Lithium addition to neuroleptic treatment in chronic schizophrenia: a randomized, double‐blind, placebo‐controlled, cross‐over study

Takeshi Terao, T. Oga, Satomi Nozaki, +5

Acta Psychiatrica Scandinavica

Discovery of orally bioavailable cyclohexanol-based NR2B-selective NMDA receptor antagonists with analgesic activity utilizing a scaffold hopping approach

Kosuke Anan, Moriyasu Masui, Shinichiro Hara, +9

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBiochemistryPain MedicineMedicineNatural Sciences +11