Toshiyuki Sakaeda

MDR1 Genotype-Related Pharmacokinetics of Digoxin After Single Oral Administration in Healthy Japanese Subjects

Toshiyuki Sakaeda, Tsutomu Nakamura, Masanori Horinouchi et al. · Pharmaceutical Research · 2001 · 321 citations

Medicine, Pharmacokinetics, Pharmacology +6

Effect of the mutation (C3435T) at exon 26 of the <i>MDR1</i> gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects

Tsutomu Nakamura, Toshiyuki Sakaeda, Masanori Horinouchi et al. · Clinical Pharmacology & Therapeutics · 2002 · 260 citations

Life Sciences, Genetics, Molecular Biology +12

Real-Time Quantitative Polymerase Chain Reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA Levels in Caco-2 Cell Lines, Human Duodenal Enterocytes, Normal Colorectal Tissues, and Colorectal Adenocarcinomas

Tsutomu Nakamura, Toshiyuki Sakaeda, Nobuko Ohmoto et al. · Drug Metabolism and Disposition · 2002 · 137 citations

Medicine, Molecular Biology, Pharmacology +14

Human Group IIA Secretory Phospholipase A2 Induces Neuronal Cell Death via Apoptosis

Tatsurou Yagami, Keiichi Ueda, Kenji Asakura et al. · Molecular Pharmacology · 2002 · 131 citations

Life Sciences, Neurobiology, Pharmacology +17

Effects of Polymorphisms of MDR1, MRP1, and MRP2 Genes on Their mRNA Expression Levels in Duodenal Enterocytes of Healthy Japanese Subjects.

Yuka Moriya, Tsutomu Nakamura, Masanori Horinouchi et al. · Biological and Pharmaceutical Bulletin · 2002 · 128 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13