Mikio Kakumoto

MDR1 Genotype-Related Pharmacokinetics of Digoxin After Single Oral Administration in Healthy Japanese Subjects

Toshiyuki Sakaeda, Tsutomu Nakamura, Masanori Horinouchi et al. · Pharmaceutical Research · 2001 · 321 citations

Medicine, Pharmacokinetics, Pharmacology +6

Citrus auraptene exerts dose-dependent chemopreventive activity in rat large bowel tumorigenesis: the inhibition correlates with suppression of cell proliferation and lipid peroxidation and with induction of phase II drug-metabolizing enzymes.

Takuji Tanaka, Kohei Kawabata, Mikio Kakumoto et al. · PubMed · 1998 · 130 citations · Full text

Medicine, Pharmacology, Toxicology +12

Intravenous Infusion of an Antisense Oligonucleotide Results in Exon Skipping in Muscle Dystrophin mRNA of Duchenne Muscular Dystrophy

Yasuhiro Takeshima, Mariko Yagi, Hiroko Wada et al. · Pediatric Research · 2006 · 100 citations

Medicine, Molecular Biology, Molecular Genetics +14

Effect of micafungin on cytochrome P450 3A4 and multidrug resistance protein 1 activities, and its comparison with azole antifungal drugs

Toshiyuki Sakaeda, Koichi Iwaki, Mikio Kakumoto et al. · Journal of Pharmacy and Pharmacology · 2005 · 99 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Effects of Acid and Lactone Forms of Eight HMG-CoA Reductase Inhibitors on CYP-Mediated Metabolism and MDR1-Mediated Transport

Toshiyuki Sakaeda, Hideki Fujino, Chiho Komoto et al. · Pharmaceutical Research · 2005 · 93 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17