Mark T. Goulet

[¹⁸F]MK-9470, a positron emission tomography (PET) tracer for<i>in vivo</i>human PET brain imaging of the cannabinoid-1 receptor

H. Donald Burns, Koen Van Laere, Sandra Sanabria Bohórquez et al. · Proceedings of the National Academy of Sciences · 2007 · 311 citations · Full text

Structure-Activity Relations of Successful Pharmacologic Chaperones for Rescue of Naturally Occurring and Manufactured Mutants of the Gonadotropin-Releasing Hormone Receptor

Jo Ann Janovick, Mark T. Goulet, Eugene N. Bush et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 137 citations

Discovery of <i>N</i>-[(1<i>S</i>,2<i>S</i>)-3-(4-Chlorophenyl)-2- (3-cyanophenyl)-1-methylpropyl]-2-methyl-2- {[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), a Novel, Acyclic Cannabinoid-1 Receptor Inverse Agonist for the Treatment of Obesity

Linus S. Lin, Thomas J. Lanza, James P. Jewell et al. · Journal of Medicinal Chemistry · 2006 · 122 citations · Full text

Cannabis Use, Molecular Pharmacology, Medicinal Chemistry +15

Structure-dependent Impairment of Intracellular Apolipoprotein E4 Trafficking and Its Detrimental Effects Are Rescued by Small-molecule Structure Correctors

Jens Brodbeck, Jim McGuire, Zhaoping Liu et al. · Journal of Biological Chemistry · 2011 · 102 citations · Full text

Proteinlipid Interaction, Structure-dependent Impairment, Detrimental Effects +22

Antiobesity Efficacy of a Novel Cannabinoid-1 Receptor Inverse Agonist, N-[(1 S,2 S)-3-(4-Chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), in Rodents

Tung M. Fong, Xiao-Ming Guan, Donald J. Marsh et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 100 citations