Amy E. Mercer

Evidence for the Involvement of Carbon-centered Radicals in the Induction of Apoptotic Cell Death by Artemisinin Compounds

Amy E. Mercer, James L. Maggs, Xiaoming Sun et al. · Journal of Biological Chemistry · 2007 · 193 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

The Role of Heme and the Mitochondrion in the Chemical and Molecular Mechanisms of Mammalian Cell Death Induced by the Artemisinin Antimalarials

Amy E. Mercer, Ian M. Copple, James L. Maggs et al. · Journal of Biological Chemistry · 2010 · 166 citations · Full text

Pharmacy, Pharmacology, Toxicology +17

Evidence for a Common Non‐Heme Chelatable‐Iron‐Dependent Activation Mechanism for Semisynthetic and Synthetic Endoperoxide Antimalarial Drugs

Paul A. Stocks, Patrick G. Bray, Victoria Barton et al. · Angewandte Chemie International Edition · 2007 · 130 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Antimalarial and Antitumor Evaluation of Novel C-10 Non-Acetal Dimers of 10β-(2-Hydroxyethyl)deoxoartemisinin

J.P. Jeyadevan, Patrick G. Bray, James Chadwick et al. · Journal of Medicinal Chemistry · 2004 · 96 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance

Paul M. O’Neill, Richard K. Amewu, Susan A. Charman et al. · Nature Communications · 2017 · 63 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16