Ian M. Copple

Physical and Functional Interaction of Sequestosome 1 with Keap1 Regulates the Keap1-Nrf2 Cell Defense Pathway

Ian M. Copple, Adam Lister, Akua D. Obeng et al. · Journal of Biological Chemistry · 2010 · 265 citations · Full text

Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy

Adam Lister, Taoufik Nedjadi, Neil R. Kitteringham et al. · Molecular Cancer · 2011 · 238 citations · Full text

Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity—implications for therapeutic targeting of Nrf2

Ian M. Copple, Holly K. Bryan, George T. Edge et al. · Free Radical Biology and Medicine · 2014 · 227 citations · Full text

The Role of Heme and the Mitochondrion in the Chemical and Molecular Mechanisms of Mammalian Cell Death Induced by the Artemisinin Antimalarials

Amy E. Mercer, Ian M. Copple, James L. Maggs et al. · Journal of Biological Chemistry · 2010 · 164 citations · Full text

Mitophagy, Mitochondrial Dysfunction, Malaria +21

The hepatotoxic metabolite of acetaminophen directly activates the Keap1‐Nrf2 cell defense system†

Ian M. Copple, Christopher E. Goldring, Rosalind E. Jenkins et al. · Hepatology · 2008 · 131 citations