Marie-Pierre de Béthune

Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants

Kalyan Das, Arthur D. Clark, Paul Lewi et al. · Journal of Medicinal Chemistry · 2004 · 511 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17

Efficacy and safety of darunavir-ritonavir compared with that of lopinavir-ritonavir at 48 weeks in treatment-experienced, HIV-infected patients in TITAN: a randomised controlled phase III trial

José Valdez Madruga, Daniel Berger, Marilyn McMurchie et al. · The Lancet · 2007 · 332 citations

Pharmacy, Infectious Diseases, Pharmacotherapy +12

Evolution of anti-HIV drug candidates. Part 3: diarylpyrimidine (DAPY) analogues

Donald Ludovici, Bart L. De Corte, Michael J. Kukla et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 185 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Antiviral activity of Hawaiian medicinal plants against human immunodeficiency Virus Type-1 (HIV-1)

Christopher P. Locher, Myriam Witvrouw, Marie-Pierre de Béthune et al. · Phytomedicine · 1996 · 116 citations · Full text

Life Sciences, Botany, Infectious Diseases +16

Evolution of anti-HIV drug candidates. Part 1: From α-Anilinophenylacetamide (α-APA) to imidoyl thiourea (ITU)

Donald Ludovici, Michael J. Kukla, Philip G. Grous et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 81 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12