Jae Won Soh

Increased expression of cyclin D1 in a murine mammary epithelial cell line induces p27kip1, inhibits growth, and enhances apoptosis.

Edward K. Han, Martin Begemann, Alessandro Sgambato et al. · PubMed · 1996 · 143 citations

Breast Oncology, Cyclin D1, Apoptosis +18

Antiproliferative effects of S-allylmercaptocysteine on colon cancer cells when tested alone or in combination with sulindac sulfide.

Haim Shirin, Joana Pinto, Yuichi Kawabata et al. · PubMed · 2001 · 141 citations

Chemoprevention Strategy, Oxidative Stress, Medicinal Chemistry +16

Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1.

Jae Won Soh, Y. K. Mao, Min‐Gul Kim et al. · PubMed · 2000 · 134 citations

Chemoprevention Strategy, Sulindac Derivatives, Apoptosis +20

Paradoxical increase in retinoblastoma protein in colorectal carcinomas may protect cells from apoptosis.

Hirofumi Yamamoto, Jae Won Soh, Takushi Monden et al. · PubMed · 1999 · 75 citations

Apoptosis, Retinoblastoma Protein, Pathology +17

Novel target for induction of apoptosis by cyclo-oxygenase-2 inhibitor SC-236 through a protein kinase C-β1-dependent pathway

Xiaohua Jiang, Shiu‐Kum Lam, Marie C.M. Lin et al. · Oncogene · 2002 · 73 citations

Signal Transduction, Cell Regulation, Medicine +10