Lucy M. Rose

Mechanisms of action of 6-thioguanine, 6-mercaptopurine, and 8-azaguanine.

J. Arly Nelson, J W Carpenter, Lucy M. Rose et al. · PubMed · 1975 · 244 citations

Molecular Pharmacology, Biosynthesis, Biochemistry +11

Effects of 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5'-triphosphate.

William B. Parker, Sue C. Shaddix, Chao‐Sung Chang et al. · PubMed · 1991 · 210 citations

Chemoprevention Strategy, Human Ribonucleotide Reductase, Molecular Biology +26

Metabolism and Metabolic Actions of 6-Methylpurine and 2-Fluoroadenine in Human Cells

William B. Parker, Paula W. Allan, Sue C. Shaddix et al. · Biochemical Pharmacology · 1998 · 108 citations

Biochemistry, Human Cells, Medicine +11

Comparison of the mechanism of cytotoxicity of 2-chloro-9-(2-deoxy-2- fluoro-beta-D-arabinofuranosyl)adenine, 2-chloro-9-(2-deoxy-2-fluoro- beta-D-ribofuranosyl)adenine, and 2-chloro-9-(2-deoxy-2,2-difluoro- beta-D-ribofuranosyl)adenine in CEM cells.

William B. Parker, Sue C. Shaddix, Lucy M. Rose et al. · PubMed · 1999 · 76 citations

Chemoprevention Strategy, Apoptosis, Cell Death +20

THE MECHANISM OF ACTION OF 3‐DEAZAURIDINE IN TUMOR CELLS SENSITIVE AND RESISTANT TO ARABINOSYLCYTOSINE^*

R W Brockman, Sue C. Shaddix, Marilyn Williams et al. · Annals of the New York Academy of Sciences · 1975 · 72 citations

Pyrimidine Ribonucleotides, Chemoprevention Strategy, Cellular Pharmacology +17