Sue C. Shaddix

Effects of 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5'-triphosphate.

William B. Parker, Sue C. Shaddix, Chao‐Sung Chang et al. · PubMed · 1991 · 210 citations

Chemoprevention Strategy, Human Ribonucleotide Reductase, Molecular Biology +26

Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RNA template for the evaluation of antiretroviral drugs

William B. Parker, E. Lucile White, Sue C. Shaddix et al. · Journal of Biological Chemistry · 1991 · 133 citations · Full text

Immunology, Molecular Biology, Antiviral Drug +20

.alpha.-(N)-Formylheteroaromatic thiosemicarbazones. Inhibition of tumor-derived ribonucleoside diphosphate reductase and correlation with in vivo antitumor activity

Frederic A. French, Erwin J. Blanz, Sue C. Shaddix et al. · Journal of Medicinal Chemistry · 1974 · 130 citations

Chemoprevention Strategy, Altmetric Attention Score, Pharmacotherapy +20

Metabolism and Metabolic Actions of 6-Methylpurine and 2-Fluoroadenine in Human Cells

William B. Parker, Paula W. Allan, Sue C. Shaddix et al. · Biochemical Pharmacology · 1998 · 108 citations

Biochemistry, Human Cells, Medicine +11

Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases

E. Lucile White, William B. Parker, Lisa J. Macy et al. · Biochemical and Biophysical Research Communications · 1989 · 100 citations

Medicine, Human Polymerases, Human Retrovirus +7