William B. Parker

Effects of 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5'-triphosphate.

William B. Parker, Sue C. Shaddix, Chao‐Sung Chang et al. · PubMed · 1991 · 210 citations

Medicine, Molecular Biology, Pharmacology +13

Failure of cAMP agonists to activate rescued ΔF508 CFTR in CFBE41o^–airway epithelial monolayers

Zsuzsa Bebők, James F. Collawn, John Wakefield et al. · The Journal of Physiology · 2005 · 190 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Interaction of 2-halogenated dATP analogs (F, Cl, and Br) with human DNA polymerases, DNA primase, and ribonucleotide reductase.

William B. Parker, Ashok R. Bapat, Jia-Xiang Shen et al. · Molecular Pharmacology · 1988 · 144 citations

Life Sciences, Biochemistry, Molecular Biology +17

Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RNA template for the evaluation of antiretroviral drugs

William B. Parker, E. Lucile White, Sue C. Shaddix et al. · Journal of Biological Chemistry · 1991 · 133 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Metabolism and Metabolic Actions of 6-Methylpurine and 2-Fluoroadenine in Human Cells

William B. Parker, Paula W. Allan, Sue C. Shaddix et al. · Biochemical Pharmacology · 1998 · 110 citations

Life Sciences, Biochemistry, Pharmacology +5