Sandeep Mahajan

Rational Design and Synthesis of a Novel Anti-leukemic Agent Targeting Bruton′s Tyrosine Kinase (BTK), LFM-A13 [α-Cyano-β-Hydroxy-β-Methyl-N-(2,5-Dibromophenyl)Propenamide]

Sandeep Mahajan, Sutapa Ghosh, E. Sudbeck et al. · Journal of Biological Chemistry · 1999 · 189 citations · Full text

Structure-based design of specific inhibitors of Janus kinase 3 as apoptosis-inducing antileukemic agents.

E. Sudbeck, Xingping Liu, Rama Krishna Narla et al. · PubMed · 1999 · 165 citations

Drug Target, Bioorganic Chemistry, Apoptosis +21

BTK as a Mediator of Radiation-Induced Apoptosis in DT-40 Lymphoma B Cells

Fatih M. Uckun, Kevin G. Waddick, Sandeep Mahajan et al. · Science · 1996 · 163 citations

Tyrosine Kinase, Apoptosis, Immunology +17

Src Family Protein Tyrosine Kinases Induce Autoactivation of Bruton's Tyrosine Kinase

Sandeep Mahajan, Joseph Fargnoli, Anne L. Burkhardt et al. · Molecular and Cellular Biology · 1995 · 150 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +11

PIM1 Protein Kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells

Fengxue Zhang, Zanna Beharry, Thurl E. Harris et al. · Cancer Biology & Therapy · 2009 · 136 citations · Full text

Signal Transduction, Cell Regulation, Fdcp1 Cells +15