Elevated serum levels of IFN-γ, IL-4 and TNF-α/unelevated serum levels of IL-10 in patients with demyelinating diseases during the acute stage

Kiyoto Hohnoki, Atsushi Inoue, Chang-Sung Koh

Journal of Neuroimmunology

Clinical ImmunologyAutoimmune DiseaseAcute StageMedicineImmunodeficiencies +6

Anti-IL-12 antibody prevents the development and progression of multiple sclerosis-like relapsing–remitting demyelinating disease in NOD mice induced with myelin oligodendrocyte glycoprotein peptide

Motoki Ichikawa, Chang-Sung Koh, Atsushi Inoue, +7

Journal of Neuroimmunology

Immune RegulationImmunologyImmunotherapyImmune DysregulationNeuroinflammation +15

Novel Immunosuppressive Therapy by M2000 in Experimental Multiple Sclerosis

Abbas Mirshafiey, Hidenori Matsuo, Shunya Nakane, +3

Immunopharmacology and Immunotoxicology

Role of Individual T-Cell Epitopes of Theiler’s Virus in the Pathogenesis of Demyelination Correlates with the Ability To Induce a Th1 Response

Robert L. Yauch, Joann P. Palma, Hiroyuki Yahikozawa, +2

Journal of Virology

T-regulatory CellImmunologyAntigen ProcessingCd4 T Cell ResponsesT Cells +14

The Role of Interleukin-6 in the Expression of PD-1 and PDL-1 on Central Nervous System Cells following Infection with Theiler's Murine Encephalomyelitis Virus

Young-Hee Jin, Wanqiu Hou, Hyun Seok Kang, +2

Journal of Virology

ImmunologyPathologyImmunologic MechanismTmev InfectionImmunotherapy +15

IgG Subclass Switching Is Associated with the Severity of Experimental Autoimmune Encephalomyelitis Induced with Myelin Oligodendrocyte Glycoprotein Peptide in NOD Mice

Motoki Ichikawa, Chang-Sung Koh, Yuji Inaba, +6

Cellular Immunology

Autoimmune DiseaseMedicineImmunologyAutoimmunityAutoantibodies +8

Expression and Potential Role of Inducible Nitric Oxide Synthase in the Central Nervous System of Theiler's Murine Encephalomyelitis Virus-Induced Demyelinating Disease

Teruaki Iwahashi, Atsushi Inoue, Chang-Sung Koh, +2

Cellular Immunology

Neurological DisorderMedicineViral PathogenesisImmunologyVirology +7

Neurovascular fibrinolytic activity in normal Lewis rats and rats with cell-transferred experimental allergic encephalomyelitis

Chang-Sung Koh, Hau C. Kwaan, Philip Y. Paterson

Journal of Neuroimmunology

InflammationAllergyNeurophysiologyMedicineNeurovascular Fibrinolytic Activity +13

Role of the Programmed Death-1 (PD-1) pathway in regulation of Theiler's murine encephalomyelitis virus-induced demyelinating disease

Sho Takizawa, Tomoki Kaneyama, Sayaka Tsugane, +6

Journal of Neuroimmunology

MedicineViral PathogenesisImmunologyCell DeathAntiviral Response +5

Dimethyl fumarate suppresses Theiler’s murine encephalomyelitis virus-induced demyelinating disease by modifying the Nrf2-Keap1 pathway

Kunitoshi Kobayashi, Hiroki Tomiki, Yuji Inaba, +3

International Immunology