Concepedia

Anti-IL-12 antibody prevents the development and progression of multiple sclerosis-like relapsing–remitting demyelinating disease in NOD mice induced with myelin oligodendrocyte glycoprotein peptide

Motoki Ichikawa, Chang-Sung Koh, Atsushi Inoue, Jun Tsuyusaki, Masashi Yamazaki, Yuji Inaba, Yukio Sekiguchi, Makoto Itoh, H Yagita, Atsushi Komiyama

Journal of Neuroimmunology · 2000 · 64 citations · 35 references

DOI

Concepts

References

35

Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes

Giorgio Trinchieri · Blood · 1994 · 1.1K citations · Full text

, , +17

Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein.

Christopher Linington, Monika Bradl, Hans Lassmann et al. · PubMed · 1988 · 721 citations

, , +16

A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H‐2<sup>b</sup> mice: Fine specificity and T cell receptor Vβ expression of encephalitogenic T cells

Itzhack Mendel, Nicole Kerlero de Rosbo, Avraham Ben‐Nun · European Journal of Immunology · 1995 · 604 citations

, , +17

Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12.

John P. Leonard, K E Waldburger, Samuel J. Goldman · The Journal of Experimental Medicine · 1995 · 551 citations · Full text

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Interleukin‐12 is required for interferon‐γ production and lethality in lipopolysaccharide‐induced shock in mice

Maria Wysocka, Marek Kubin, Leda Quércia Vieira et al. · European Journal of Immunology · 1995 · 475 citations

, , +17