TRAF6 is a T cell–intrinsic negative regulator required for the maintenance of immune homeostasis

Carolyn G. King, Takashi Kobayashi, Pedro J. Cejas, +8

Nature Medicine

InflammationImmune HomeostasisAdaptive Immune SystemImmune Cell DevelopmentImmunology +11

TNF-related weak inducer of apoptosis receptor, a TNF receptor superfamily member, activates NF-κB through TNF receptor-associated factors

Song-Yi Han, Kwiyeom Yoon, Kyunghye Lee, +5

Biochemical and Biophysical Research Communications

InflammationCytokineSignal TransductionSignaling PathwayApoptosis +9

PIAS3 Suppresses NF-κB-mediated Transcription by Interacting with the p65/RelA Subunit

Hyun Duk Jang, Kwiyeom Yoon, Young Joo Shin, +2

Journal of Biological Chemistry

Molecular RegulationGeneticsImmunologyCell DeathTnf Receptor-associated Factors +14

Inactivation of Glycogen Synthase Kinase-3β Is Required for Osteoclast Differentiation

Hyun Duk Jang, Ji Hye Shin, Doo Ri Park, +8

Journal of Biological Chemistry

Comprehensive genome- and transcriptome-wide analyses of mutations associated with microsatellite instability in Korean gastric cancers

Kwiyeom Yoon, Sunghoon Lee, Tae‐Su Han, +15

Genome Research

Somatic VariantGenetic AberrationsTumor HeterogeneityMedicineGenetics +12

PPP1R1B-STARD3 chimeric fusion transcript in human gastric cancer promotes tumorigenesis through activation of PI3K/AKT signaling

S M Yun, Kwiyeom Yoon, Sunghoon Lee, +12

Oncogene

Tumor BiologyCell SignalingMedicineTumor SuppressorRadiation Oncology +4

TRAF6 deficiency promotes TNF-induced cell death through inactivation of GSK3β

Kwiyeom Yoon, Eunjung Jung, S R Lee, +3

Cell Death and Differentiation

InflammationCytokineSignal TransductionSignaling PathwayCell Regulation +8

Direct interaction of Smac with NADE promotes TRAIL-induced apoptosis

Kwiyeom Yoon, Hyun Duk Jang, Soo Young Lee

Biochemical and Biophysical Research Communications

Signal TransductionSignaling PathwayNatural SciencesApoptosisDirect Interaction +8

TRAF6-mediated regulation of the PI3 kinase (PI3K)–Akt–GSK3β cascade is required for TNF-induced cell survival

Kwiyeom Yoon, Eun Joo Jung, Soo Young Lee

Biochemical and Biophysical Research Communications

Pi3 KinaseSignal TransductionSignaling PathwayCell RegulationImmune Regulation +8

Homozygous deletions at 3p22, 5p14, 6q15, and 9p21 result in aberrant expression of tumor suppressor genes in gastric cancer

Bona Lee, Kwiyeom Yoon, Sunghoon Lee, +9

Genes Chromosomes and Cancer