John C. Hutton

Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene

Robert S. Jackson, John W.M. Creemers, Shinya Ohagi et al. · Nature Genetics · 1997 · 1.2K citations

Obesity, Metabolic Syndrome, Energy Homeostasis +10

The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes

Janet M. Wenzlau, Kirstine Juhl, Liping Yu et al. · Proceedings of the National Academy of Sciences · 2007 · 990 citations · Full text

Metabolic Syndrome, Zinc Transporter Znt8, Microarray Expression Profiling +15

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

Maki Nakayama, Norio Abiru, Hiroaki Moriyama et al. · Nature · 2005 · 741 citations · Full text

Type 1, Signal Transduction, Insulin Epitope +12

The stimulus-secretion coupling of glucose-induced insulin release

W. J. Malaisse, John C. Hutton, S Kawazu et al. · Diabetologia · 1979 · 420 citations · Full text

Stimulus-secretion Coupling, Insulin Management, Physiology +5

Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic β cell via two distinct site-specific endopeptidases

Howard W. Davidson, Christopher J. Rhodes, John C. Hutton · Nature · 1988 · 405 citations

Protein Secretion, Intraorganellar Calcium, Molecular Physiology +10