Hiroaki Moriyama

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

Maki Nakayama, Norio Abiru, Hiroaki Moriyama et al. · Nature · 2005 · 741 citations · Full text

Type 1, Signal Transduction, Insulin Epitope +12

Evidence for a primary islet autoantigen (preproinsulin 1) for insulitis and diabetes in the nonobese diabetic mouse

Hiroaki Moriyama, Norio Abiru, Johanna Paronen et al. · Proceedings of the National Academy of Sciences · 2003 · 198 citations · Full text

Immunology, Pathology, Primary Islet Autoantigen +17

Induction and acceleration of insulitis/diabetes in mice with a viral mimic (polyinosinic-polycytidylic acid) and an insulin self-peptide

Hiroaki Moriyama, Wen Li, Norio Abiru et al. · Proceedings of the National Academy of Sciences · 2002 · 128 citations · Full text

Immunology, Pathology, Antigen Processing +19

Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23

Edwin Liu, Hiroaki Moriyama, Norio Abiru et al. · Journal of Clinical Investigation · 2002 · 93 citations · Full text

Upregulation of the Mammalian Target of Rapamycin Complex 1 Pathway by Ras Homolog Enriched in Brain in Pancreatic β-Cells Leads to Increased β-Cell Mass and Prevention of Hyperglycemia

Suirin Hamada, Kenta Hara, Takeshi Hamada et al. · Diabetes · 2009 · 92 citations · Full text