Ying-Chi Chu

Mapping the Functional Surface of Insulin by Design: Structure and Function of a Novel A-Chain Analogue

Qing‐Xin Hua, Shi-Quan Hu, Bruce H. Frank et al. · Journal of Molecular Biology · 1996 · 109 citations

Biochemistry, Functional Surface, Protein Folding +9

How Insulin Binds: the B-Chain α-Helix Contacts the L1 β-Helix of the Insulin Receptor

Kun Huang, Bin Xu, Shi-Quan Hu et al. · Journal of Molecular Biology · 2004 · 74 citations

Signal Transduction, Molecular Physiology, Biochemistry +9

Diabetes-Associated Mutations in Insulin:  Consecutive Residues in the B Chain Contact Distinct Domains of the Insulin Receptor^,

Bin Xu, Shi-Quan Hu, Ying-Chi Chu et al. · Biochemistry · 2004 · 59 citations

Diabetes-Associated Mutations in Human Insulin:  Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin<i>Wakayama</i>^,

Zhu‐li Wan, Kun Huang, Bin Xu et al. · Biochemistry · 2005 · 49 citations

Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures

Qing‐Xin Hua, Shi-Quan Hu, Wenhua Jia et al. · Journal of Molecular Biology · 1998 · 49 citations

Protein Function, Protein Folding, Medicine +5