Highly Enantioselective Reformatsky Reaction of Ketones:  Chelation-Assisted Enantioface Discrimination

Akio Ojida, Toru Yamano, Naohiro Taya, +1

Organic Letters

EngineeringCinchona AlkaloidsNatural SciencesDiversity-oriented SynthesisEnantioface Discrimination +9

Enantioselective hydrogenation of β-keto esters catalyzed by P-chiral bis(dialkylphosphino)ethanes-Ru(II)

Toru Yamano, Naohiro Taya, Mitsuru Kawada, +2

Tetrahedron Letters

EngineeringOrganic ChemistryCatalysisP-chiral BisChemistry +2

Functional monomers and polymers, 129. Asymmetric robinson cyclization reaction catalyzed by polymer‐bound <scp>L</scp>‐proline

Koichi Kondo, Toru Yamano, Kiichi Takemoto

Die Makromolekulare Chemie

EngineeringOrganic ChemistryChemistryPolymersL ‐Proline +16

Synthesis of a Novel Series of Benzocycloalkene Derivatives as Melatonin Receptor Agonists

K. Fukatsu, Osamu Uchikawa, Mitsuru Kawada, +7

Journal of Medicinal Chemistry

Organic ChemistryHeterocycle ChemistryPharmaceutical ChemistryMedicinal ChemistryAmide Group +14

Approach to the stereoselective synthesis of melatonin receptor agonist Ramelteon via asymmetric hydrogenation

Toru Yamano, Masayuki Yamashita, Mari Adachi, +6

Tetrahedron Asymmetry

Medicinal ChemistryEnantioselective SynthesisBiochemistryMedicineNatural Sciences +6

Synthesis of Melatonin Receptor Agonist Ramelteon via Rh-catalyzed Asymmetric Hydrogenation of an Allylamine

Masayuki Yamashita, Toru Yamano

Chemistry Letters

Rhodium Josiphos ComplexMedicinal ChemistryEnantioselective SynthesisEngineeringBiochemistry +13

A Practical Method for Optical Resolution of Racemic Alcohols or Esters via Lipase-Catalyzed Transformation and Sulfation

Toru Yamano, Fumio Kikumoto, Shozo Yamamoto, +6

Chemistry Letters

Sulfurtrioxide Pyridine ComplexEngineeringOrganic ChemistryRacemic AlcoholsChemistry +14

Design, synthesis, and structure–activity relationships of spirolactones bearing 2-ureidobenzothiophene as acetyl-CoA carboxylases inhibitors

Makoto Kamata, Satoshi Endo, Mitsuo Yamamoto, +13

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryDiversity Oriented SynthesisBiochemistryNatural SciencesMedicine +6

Practical synthesis of (R)-(+)-6-(1,4-dimethoxy-3-methyl-2-naphthyl)-6-(4-hydroxyphenyl)hexanoic acid: a key intermediate for a therapeutic drug for neurodegenerative diseases

Tatsuya Ito, Tomomi Ikemoto, Toru Yamano, +2

Tetrahedron Asymmetry

Medicinal ChemistryNeurodegenerative DiseasesHexanoic AcidEngineeringNatural Sciences +8

Optically Active Cyclohexene Derivative as a New Antisepsis Agent: An Efficient Synthesis of Ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242)

Masami Yamada, Takashi Ichikawa, Toru Yamano, +4

Chemical and Pharmaceutical Bulletin