Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease

Øyvind Molberg, Stephen N. McAdam, Roman Körner, +10

Nature Medicine

InflammationAutoimmune DiseaseMucosal ImmunologyCeliac DiseaseImmunology +9

A functional and structural basis for TCR cross-reactivity in multiple sclerosis

Heather Lang, Helle J. Jacobsen, Shinji Ikemizu, +11

Nature Immunology

Tcr Cross-reactivityNeurological DisorderMedicineNeurological FunctionImmune Regulation +10

A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor

Lars Siim Madsen, Ellen Andersson, Liselotte Jansson, +9

Nature Genetics

Autoimmune DiseaseMedicineT-regulatory CellImmune RegulationImmunology +9

Mice lacking all conventional MHC class II genes

Lars Siim Madsen, Nathalie Labrecque, Jan Engberg, +5

Proceedings of the National Academy of Sciences

Functional epistasis on a common MHC haplotype associated with multiple sclerosis

Jon Waarst Gregersen, Kamil R. Kranc, Xiayi Ke, +6

Nature

HistocompatibilityCommon Mhc HaplotypeImmunogeneticsAutoimmune DiseaseMedicine +12

Selective positive modulation of the SK3 and SK2 subtypes of small conductance Ca²⁺‐activated K⁺channels

Charlotte Hougaard, Birgitte L. Eriksen, Sine W. Jørgensen, +5

British Journal of Pharmacology

Definition of MHC and T cell receptor contacts in the HLA-DR4restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice

Ellen Andersson, Bjarke Endel Hansen, Helle J. Jacobsen, +9

Proceedings of the National Academy of Sciences

Pre-clinical evaluation of novel mucoadhesive bilayer patches for local delivery of clobetasol-17-propionate to the oral mucosa

Helen Colley, Zulfahami Said, Martin E. Santocildes‐Romero, +7

Biomaterials

Tissue EngineeringRegenerative MedicineLocal DeliveryProlonged AdhesionNovel Mucoadhesive Patches +13

The Small Molecule NS11021 Is a Potent and Specific Activator of Ca2+-Activated Big-Conductance K+ Channels

Bo Hjorth Bentzen, Antônio Egídio Nardi, Kirstine Calløe, +3

Molecular Pharmacology

Efficacy and safety of a novel mucoadhesive clobetasol patch for treatment of erosive oral lichen planus: A phase 2 randomized clinical trial

Michael T. Brennan, Lars Siim Madsen, Deborah Saunders, +36

Journal of Oral Pathology and Medicine