Chuen Chan

Photoinactivation of human erythrocyte enzymes by α‐terthienyl and phenylheptatriyne, naturally occurring compounds in the asteraceae

Ei YAMAMOTO, Chi-Kit Wat, W.Donald MacRae et al. · FEBS Letters · 1979 · 28 citations

Human Erythrocyte Enzymes, Biochemistry, Photochemistry +8

The Squalestatins:  Decarboxy and 4-Deoxy Analogues as Potent Squalene Synthase Inhibitors

Chuen Chan, Daniele Andreotti, Brian J. Cox et al. · Journal of Medicinal Chemistry · 1996 · 22 citations

Medicinal Chemistry, Biosynthesis, Natural Product Synthesis +15

The squalestatins: potent inhibitors of squalene synthase. The role of the tricarboxylic acid moiety.

Nigel S. Watson, Richard Bell, Chuen Chan et al. · Bioorganic & Medicinal Chemistry Letters · 1993 · 18 citations

Medicinal Chemistry, Biosynthesis, Biochemistry +12

The squalestatins: C-3 Decarboxylation studies and rearrangement to the 6,8-dioxabicyclo[3.2.1]octane ring system

Chuen Chan, Graham G. A. Inglis, Panayiotis A. Procopiou et al. · Tetrahedron Letters · 1993 · 15 citations

Bioorganic Chemistry, C-3 Decarboxylation Studies, Biochemistry +10

The Squalestatins: Synthesis and Biological Activity of Some C3-Modified Analogs; Replacement of a Carboxylic Acid or Methyl Ester with an Isoelectronic Heterocyclic Functionality

Mark J. Bamford, Chuen Chan, Andrew Craven et al. · Journal of Medicinal Chemistry · 1995 · 14 citations · Full text

Pharmaceutical Science, S1 Analogues, Pharmaceutical Chemistry +18