Nigel S. Watson - Concepedia

Author

Nigel S. Watson

Also Known As

M.A. Convery, N S Watson, N Watson, N. S. WATSON, N.S. Watson, NIGEL S. WATSON, Najhayne Watson, Nell Watson, Nigel S Watson, Nigel S. Watson

Publications

1.1K

Citations

H-Index

Concepts

All Affiliations

GlaxoSmithKline (United Kingdom)GlaxoSmithKline (United States)Age UK GlaxoSmithKline (Brazil)Middlesex University

About

Nigel S. Watson is an author at GlaxoSmithKline (United Kingdom) specializing in natural sciences, pharmacology, and medicinal chemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	14	20	628
2	Medicine	13	16	589
3	Biochemistry	13	18	598
4	Biomolecular Engineering	5	5	101
5	Engineering	4	4	59

Nigel S. Watson

Publications

978

Citations

H-Index

Page 1

	Year	Citations
Squalestatin 1, a potent inhibitor of squalene synthase, which lowers serum cholesterol in vivo. A.J. Baxter, Barbara Fitzgerald, Julie L. Hutson, Journal of Biological Chemistry Molecular PharmacologyMedicinal ChemistryBiosynthesisCholesterol BiosynthesisLipid Synthesis	1992	208
The squalestatins, novel inhibitors of squalene synthase produced by a species of Phoma. II. Structure elucidation. Philip J. Sidebottom, Rona M. Highcock, S. J. Lane, The Journal of Antibiotics	1992	153
Factor Xa Inhibitors: S1 Binding Interactions of a Series of <i>N</i>-{(<i>3S</i>)-1-[(<i>1S</i>)-1-Methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides Chuen Chan, Alan D. Borthwick, David Brown, Journal of Medicinal Chemistry Pharmaceutical ScienceDrug TargetPharmacotherapyChemical BiologyPharmaceutical Chemistry	2007	49
Structure- and property-based design of factor Xa inhibitors: Pyrrolidin-2-ones with acyclic alanyl amides as P4 motifs Robert J. Young, Matthew Campbell, Alan D. Borthwick, Bioorganic & Medicinal Chemistry Letters Combinatorial ChemistryMedicinal ChemistryPharmaceutical ChemistryBiochemistryAcyclic Alanyl Amides	2006	40
Preparation of the 7-oxo-4-oxa-1-azabicyclo[3.2.0]hept-2-ene system and the reversible cleavage of its oxazoline ring Peter C. Cherry, C. E. NEWALL, Nigel S. Watson Journal of the Chemical Society Chemical Communications Organic ChemistryChemistryHeterocycle ChemistryChemical DerivativePharmaceutical Chemistry	1978	33
Sulfonamide-related conformational effects and their importance in structure-based design Stefan Senger, Chuen Chan, M.A. Convery, Bioorganic & Medicinal Chemistry Letters Conformational StudySulfonamide-related Conformational EffectsChemistryCrystallographyCrystal Structure Design	2007	31
The Squalestatins: Inhibitors of Squalene Synthase. Enzyme Inhibitory Activities and <i>in</i> <i>Vivo</i> Evaluation of C3-Modified Analogues Panayiotis A. Procopiou, Brian J. Cox, Barrie E. Kirk, Journal of Medicinal Chemistry Chemical BiologyPharmaceutical ChemistryMedicinal ChemistryBiosynthesisSqualene Synthase	1996	30
Design and synthesis of orally active pyrrolidin-2-one-based factor Xa inhibitors Nigel S. Watson, David Brown, Matthew Campbell, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryPharmaceutical ScienceBiochemistryMedicineNatural Sciences	2006	30
Structure and property based design of factor Xa inhibitors: Pyrrolidin-2-ones with biaryl P4 motifs Robert J. Young, Alan D. Borthwick, David Brown, Bioorganic & Medicinal Chemistry Letters Biaryl P4 MotifsCombinatorial ChemistryMedicinal ChemistryBiochemistryNatural Sciences	2007	29
Inhibitors of cholesterol biosynthesis. 2. 3,5-Dihydroxy-7-(N-pyrrolyl)-6-heptenoates, a novel series of HMG-CoA reductase inhibitors Panayiotis A. Procopiou, C. D. DRAPER, Julie L. Hutson, Journal of Medicinal Chemistry	1993	29

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