Ronald Wolin

Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: Synthesis and preliminary SAR analysis

Laurent Gomez, Michael D. Hack, Jiejun Wu et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 100 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

(+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5<i>H</i>-benzo[5,6]cyclohepta[1,2-<i>b</i>]- pyridin-11(<i>R</i>)-yl)-1-piperidinyl]-2-oxo-ethyl]-1-piperidinecarboxamide (SCH-66336):  A Very Potent Farnesyl Protein Transferase Inhibitor as a Novel Antitumor Agent

F. George Njoroge, Arthur G. Taveras, Joseph Kelly et al. · Journal of Medicinal Chemistry · 1998 · 97 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7

Electroreductive cyclization. Ketones and aldehydes tethered to .alpha.,.beta.-unsaturated esters (nitriles). Fundamental investigations

R. Daniel Little, Dennis P. Fox, Luc Van Hijfte et al. · The Journal of Organic Chemistry · 1988 · 69 citations

Natural Sciences, Chemistry, Catalysis +8

New Sequential Carbon-Carbon Bond Forming Reactions. A Samarium(II) Iodide Mediated Vinylogous Barbier Reaction Followed by an Aldol Reaction

Dennis P. Curran, Ronald Wolin · Synlett · 1991 · 63 citations

Natural Sciences, Chemistry, Catalysis +10

Synthesis and evaluation of pyrazolo[3,4-b]quinoline ribofuranosides and their derivatives as inhibitors of oncogenic Ras

Ronald Wolin, David Wang, Joseph Kelly et al. · Bioorganic & Medicinal Chemistry Letters · 1996 · 57 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9