Laurent Gomez

Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: Synthesis and preliminary SAR analysis

Laurent Gomez, Michael D. Hack, Jiejun Wu et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 99 citations

Type Ii Topoisomerases, Medicinal Chemistry, Pharmaceutical Science +10

Tetrahydroindazole inhibitors of bacterial type II topoisomerases. Part 2: SAR development and potency against multidrug-resistant strains

John J. M. Wiener, Laurent Gomez, Hariharan Venkatesan et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 73 citations

Sar Development, Medicine, Tetrahydroindazole Inhibitors +9

Discovery of Selective Phosphodiesterase 1 Inhibitors with Memory Enhancing Properties

Brian Dyck, Bryan J. Branstetter, Tawfik Gharbaoui et al. · Journal of Medicinal Chemistry · 2017 · 54 citations · Full text

Design and Synthesis of Novel and Selective Phosphodiesterase 2 (PDE2a) Inhibitors for the Treatment of Memory Disorders

Laurent Gomez, Mark E. Massari, Troy Vickers et al. · Journal of Medicinal Chemistry · 2017 · 52 citations · Full text

Psychotropic Medication, Pharmacotherapy, Chemical Biology +20

(Chloro-phenylthio-methylene)dimethylammonium chloride (CPMA) an efficient reagent for selective chlorination and bromination of primary alcohols

Laurent Gomez, Françoise Gellibert, Alain Wagner et al. · Tetrahedron Letters · 2000 · 34 citations

Chemical Engineering, Dimethylammonium Chloride, Engineering +5