John Milton

Structural Basis for the Resilience of Efavirenz (DMP-266) to Drug Resistance Mutations in HIV-1 Reverse Transcriptase

Jingshan Ren, John Milton, Kurt Weaver et al. · Structure · 2000 · 263 citations · Full text

Viral Replication, Drug Resistance Mutations, Natural Sciences +12

Structure−Activity Relationships for Pyrido-, Imidazo-, Pyrazolo-, Pyrazino-, and Pyrrolophenazinecarboxamides as Topoisomerase-Targeted Anticancer Agents

Swarna A. Gamage, Julie A. Spicer, Gordon W. Rewcastle et al. · Journal of Medicinal Chemistry · 2002 · 145 citations

Pharmaceutical Science, Pharmacotherapy, Pharmaceutical Chemistry +16

Novel Angular Benzophenazines:  Dual Topoisomerase I and Topoisomerase II Inhibitors as Potential Anticancer Agents

Nigel Vicker, Luke Burgess, Irina Chuckowree et al. · Journal of Medicinal Chemistry · 2002 · 131 citations

Medicinal Chemistry, Pharmaceutical Chemistry, Bioorganic Chemistry +15

Phenylethylthiazolylthiourea (PETT) Non-nucleoside Inhibitors of HIV-1 and HIV-2 Reverse Transcriptases

Jingshan Ren, Jonathan M. Diprose, Jonathan Warren et al. · Journal of Biological Chemistry · 2000 · 115 citations · Full text

Design of Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase with Improved Drug Resistance Properties. 1.

Andrew L. Hopkins, Jingshan Ren, John Milton et al. · Journal of Medicinal Chemistry · 2004 · 90 citations · Full text

Molecular Biology, Antiviral Drug, Quinolone Nnrtis +19