Concepedia

Author

Karl Miranda

Novartis (Switzerland)

Also Known As

Karl Miranda

11

Publications

347

Citations

9

H-Index

21

Concepts

All Affiliations

Novartis (Switzerland)Brigham Young UniversityNovartis (United States)Novartis Institutes for BioMedical ResearchRega Institute for Medical Research
KM

About

Karl Miranda is an author at Novartis (Switzerland) specializing in drug discovery, pharmacology, and medicine.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

4

4

159

2

Pharmacology

4

4

159

3

Natural Sciences

2

2

94

4

Biochemistry

2

2

94

5

Chemical Biology

1

1

41

Karl Miranda

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8

Publications

338

Citations

8

H-Index

YearCitations

A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase

Lauren G. Monovich, Richard B. Vega, Erik L. Meredith,

FEBS Letters

2009

58

Identification of Orally Available Naphthyridine Protein Kinase D Inhibitors

Erik L. Meredith, Ophelia Ardayfio, Kimberly Beattie,

Journal of Medicinal Chemistry

2010

53

Discovery and in Vivo Evaluation of Potent Dual CYP11B2 (Aldosterone Synthase) and CYP11B1 Inhibitors

Erik L. Meredith, Gary M. Ksander, Lauren G. Monovich,

ACS Medicinal Chemistry Letters

2013

46

Synthesis and Biological Evaluation of 6-(Alkyn-1-yl)furo[2,3<i>-d</i>]pyrimidin-2(3<i>H</i>)-one Base and Nucleoside Derivatives

Morris J. Robins, Karl Miranda, Vivek K. Rajwanshi,

Journal of Medicinal Chemistry

2005

46

Identification of Potent and Selective Amidobipyridyl Inhibitors of Protein Kinase D

Erik L. Meredith, Kimberly Beattie, Robin Burgis,

Journal of Medicinal Chemistry

2010

41

The Discovery of <i>N</i>-(1-Methyl-5-(trifluoromethyl)-1<i>H</i>-pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)-1<i>H</i>-indole-1-carboxamide (Acrizanib), a VEGFR-2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration

Christopher M. Adams, Karen Anderson, Gerald D. Artman,

Journal of Medicinal Chemistry

2018

36

Synthesis and Antiviral Evaluation of 6-(Alkyl-heteroaryl)furo[2,3-<i>d</i>]pyrimidin-2(3<i>H</i>)-one Nucleosides and Analogues with Ethynyl, Ethenyl, and Ethyl Spacers at C6 of the Furopyrimidine Core

Morris J. Robins, Ireneusz Nowak, Vivek K. Rajwanshi,

Journal of Medicinal Chemistry

2007

29

Discovery of Oral VEGFR-2 Inhibitors with Prolonged Ocular Retention That Are Efficacious in Models of Wet Age-Related Macular Degeneration

Erik L. Meredith, Nello Mainolfi, Stephen Poor,

Journal of Medicinal Chemistry

2015

29

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