Zsolt Szombathelyi

Cariprazine (RGH-188), a Dopamine D3 Receptor-Preferring, D3/D2 Dopamine Receptor Antagonist–Partial Agonist Antipsychotic Candidate: In Vitro and Neurochemical Profile

Béla Kiss, Attila Horváth, Zsolt Némethy et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 365 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Cariprazine (RGH-188), a potent D3/D2 dopamine receptor partial agonist, binds to dopamine D3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents

István Gyertyán, Béla Kiss, Katalin Sághy et al. · Neurochemistry International · 2011 · 147 citations

Medicine, Pharmacology, Psychiatry +13

Discovery of cariprazine (RGH-188): A novel antipsychotic acting on dopamine D3/D2 receptors

Éva Ágai-Csongor, György Domány, Katalin Nógrádi et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 92 citations · Full text

Medicine, Pharmacology, Psychiatry +12

Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: I. neurochemical characterisation of RG-15

Béla Kiss, I. Laszlovszky, Attila Horváth et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 2008 · 60 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: II. behavioural characterisation of RG-15

István Gyertyán, Katalin Sághy, Judit Laszy et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 2008 · 55 citations

Medicine, Medicinal Chemistry, Pharmacology +14