Concepedia

Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: I. neurochemical characterisation of RG-15

Béla Kiss, I. Laszlovszky, Attila Horváth, Zsolt Némethy, Eva Marina Schmidt, Gyula Bugovics, Károly Fazekas, István Gyertyán, Éva Ágai-Csongor, György Domány,

Naunyn-Schmiedeberg s Archives of Pharmacology · 2008 · 60 citations · 59 references

DOI

Concepts

References

59

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

Pierre Sokoloff, Bruno Giros, Marie‐Pascale Martres et al. · Nature · 1990 · 2.6K citations · Full text

, , +12

Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in Vivo using an inhibitor of the aromatic amino acid decarboxylase

Arvid Carlsson, James N. Davis, W. Kehr et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 1972 · 648 citations

, , +12

Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist

Maria Pilla, Sylvie Perachon, François Sautel et al. · Nature · 1999 · 568 citations

, , +13

Specific in vitro and in vivo binding of 3H-raclopride a potent substituted benzamide drug with high affinity for dopamine D-2 receptors in the rat brain

Christer Köhler, Håkan Hall, Sven Ove Ögren et al. · Biochemical Pharmacology · 1985 · 506 citations

, , +12