Katalin Sághy

Cariprazine (RGH-188), a potent D3/D2 dopamine receptor partial agonist, binds to dopamine D3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents

István Gyertyán, Béla Kiss, Katalin Sághy et al. · Neurochemistry International · 2011 · 147 citations

Medicine, Pharmacology, Psychiatry +13

Discovery of cariprazine (RGH-188): A novel antipsychotic acting on dopamine D3/D2 receptors

Éva Ágai-Csongor, György Domány, Katalin Nógrádi et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 92 citations · Full text

Medicine, Pharmacology, Psychiatry +12

Cariprazine (RGH-188), a D3-preferring dopamine D3/D2 receptor partial agonist antipsychotic candidate demonstrates anti-abuse potential in rats

Viktor Román, István Gyertyán, Katalin Sághy et al. · Psychopharmacology · 2012 · 55 citations

Medicine, Pharmacology, Psychiatry +12

Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: II. behavioural characterisation of RG-15

István Gyertyán, Katalin Sághy, Judit Laszy et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 2008 · 55 citations

Medicine, Medicinal Chemistry, Pharmacology +14

<p>Preclinical pharmacodynamic and pharmacokinetic characterization of the major metabolites of cariprazine</p>

Béla Kiss, Zsolt Némethy, Károly Fazekas et al. · Drug Design Development and Therapy · 2019 · 50 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16