Howard Y. Chen

Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass

Airu S. Chen, Donald J. Marsh, Myrna E. Trumbauer et al. · Nature Genetics · 2000 · 891 citations

Obesity, Metabolic Syndrome, Energy Homeostasis +9

Presenilin 1 is required for Notch 1 and Dll1 expression in the paraxial mesoderm

Philip C. Wong, Hui Zheng, Hua Chen et al. · Nature · 1997 · 718 citations

Notch 1, Systems Biology, Cell Biology +2

β-amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

Hui Zheng, Minghao Jiang, Myrna E. Trumbauer et al. · Cell · 1995 · 700 citations · Full text

Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism

Donald J. Marsh, Drew T. Weingarth, Dawn E. Novi et al. · Proceedings of the National Academy of Sciences · 2002 · 546 citations · Full text

Metabolic Rate, Gastrointestinal Peptide Hormone, Obesity +19

Transgenic mice harboring SV40 t-antigen genes develop characteristic brain tumors

Ralph L. Brinster, Howard Y. Chen, Albee Messing et al. · Cell · 1984 · 489 citations

Knockout Mouse, Neuro-oncology, Immunogenetics +9